PREDICTION OF UNFAVOURABLE RESPONSE TO CHECKPOINT BLOCKADE IN LUNG CANCER PATIENTS THROUGH AN INTEGRATED TUMOUR-IMMUNE EXPRESSION SCORE

Prediction of unfavourable response to checkpoint blockade in lung cancer patients through an integrated tumour-immune expression score

Background: Treatment by immune checkpoint blockade (ICB) provides a remarkable survival benefit for multiple cancer types.However, disease aggravation occurs in a proportion of patients after the first couple of treatment cycles.Methods: RNA sequencing data was retrospectively collected.6 tumour-immune related features were extracted and combined

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Reporting Characteristics in Sports Nutrition

Purpose: To examine data reporting characteristics in sports nutrition.Methods: We examined 236 papers from ten journals published in 2016.The primary outcome was statistical variance associated with treatment (SD (correct) vs.SEM or CI).Secondary outcomes included the reporting of: (a) effect sizes (Y/N); (b) outcome prioritization (Y/N; primary,

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Inelastic Dirac dark matter

Abstract Feebly interacting thermal relics are promising dark matter candidates.Among them, scenarios of Bike Accessories - Bags inelastic Dark Matter evade direct detection by suppressed elastic scattering off atomic nuclei.We introduce inelastic Dirac Dark Matter, a new model with two Dirac fermions in the MeV-GeV mass range.At feeble couplings,

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